Melanotan 2 Scientific Research


American Made Melanotan II

Melanotan II, also known as Melanotan 2 or MT-2 but different from Melanotan I, is a peptide that has a molecular mass of 1024.180 and a molecular formula of C50H69N15O9.  It has been shown through scientific study on animal test subjects to have an ability to enhance the protection against harmful ultraviolet, or UV, rays.

Melanotan II’s Functionality on a Glandular Level

The essential base of functionality according to scientific study that has been based on animal test subjects is constructed about a relationship Melanotan II has with the pituitary gland.  This pea-sized gland that is located at the bottom of the hypothalamus at the base of the brain is chiefly charged with the regulation and control of a host of processes linked to the endocrine system.  Some of these processes have been shown to include:

  • The regulation of metabolism
  • The regulation of growth
  • The control of internal temperature
  • The functionality of the thyroid gland

Melanotan II on a Level of Secretion

Specifically, the relationship that Melanotan II has with the pituitary gland is tied to secreted hormones that are known as melanocortins.  These particular hormones are responsible for the regulation of control of skin and hair pigmentation by way of a secretion known as melanin.  This expression of this secretion is initiated by the exposure of UV, or ultraviolet, rays.  When exposure to the rays happen, the secreted melanin manifests itself on the skin of the animal test subject; a process that is known as melanogenesis.  This process not only results in the darkening of the skin’s pigment, but it also leads to providing the skin with a measure of protection against the exposure to the harmful rays themselves.  A such, the process of melanogenesis plays a key role in protecting the skin against a host of various skin-based ailments that have been shown to result from extensive exposure to UV rays, up to and including certain types of skin cancers.

The main issue regarding melanogenesis is that the melanocortins that have been shown to produce melanin have an extremely short half-life that only lasts for a few minutes, thus rendering their overall effectiveness as a safeguarding agent to be limited.  However, scientific study that has been based on animal test subjects has been able to determine that the presence of Melanotan II can extend the half-life of melanocortins.  Thus, the peptide can also extend the secretion’s presence as a protective agent against harmful UV rays and the skin-related ailments that such exposure has been determined to create.  What’s more these studies have indicated that this act of Melanotan II’s functionality can be brought about even without the exposure to UV rays that would otherwise initiate the defense mechanism.  That being said, the studies have indicated that the presence of Melanotan II has shown to be more effective when UV rays are introduced as part of the research process.

Melanotan II vs. Melanotan I

Scientific study that has been based on animal test subjects has shown that Melanotan II’s overall functionality has enabled it to hold a similar resemblance to the operational mechanics of Melanotan I, which is why the two peptides sometimes have a tendency to be confused with each other.  However, comparative studies between the two peptides have noted that the overall effectiveness of Melanotan II has been shown to be significantly more efficient than its counterpart.

Melanotan II and Cancer

Scientific study that has been based on animal test subjects has been able to derive that the peptide’s ability to promote actions of melanogenesis without ultraviolet rays being present could conceptually enable it to play a vital role in lowering the likely onset of most skin cancers.  That being said, it should be noted that it has been determined that the presence of the peptide does not act as a possible deterrent against the deadliest form of skin cancer, malignant melanoma.  The reason for this is due to the fact that malignant melanoma has been shown to be caused by indirect DNA damage, and not by the presence of ultraviolet rays.

For Scientific Research Only

Although there has been an extensive amount of research and study conducted in relation to Melanotan II and its overall functionality, operational mechanics, and theorized benefits, it needs to be noted that all of the research that has been conducted and the subsequent results from such research has been solely built around the scientific study based on animal test subjects.  The peptide is only intended for the use of scientific study at this point in time.  As a result of this, any findings or observations that relate to Melanotan II’s overall functionality, mechanics, or theoretical benefits, should only be contained to the strict confines of a controlled environment such as a medical research facility or a laboratory.